Effect of 3'-amino-2',3'-dideoxycytidine on DNA replicative intermediates
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چکیده
منابع مشابه
Replication of mycoplasma virus L51. VII. Effect of chloramphenicol on the synthesis of DNA replicative intermediates.
Chloramphenicol affects several steps in the DNA replication of mycoplasma virus L51, a noncytocidal, naked, bullet-shaped virion containing circular single-stranded (SS) DNA of 1.5 X 10(6) daltons (4.5 kilobases). In the presence of chloramphenicol, adsorption was normal and parental SS DNA was converted to double-stranded replicative forms (RF), but subsequent RF leads to RF replication was i...
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15 صفحه اولCell line specific radiosensitizing effect of zalcitabine (2',3'-dideoxycytidine).
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15 صفحه اولAccumulation of Replicative Intermediates of Mitochondrial Dna in Tetrahymena Pyriformis Grown in Ethidium Bromide
The effect of growth of Tetrahymena pyriformis in ethidium bromide (EthBr) on the structure and synthesis of mitochondrial DNA (mtDNA) has been investigated. During the first 5 h of growth in EthBr, mtDNA synthesis is inhibited 95% or more. After 10-15 h, this block is partially released and large numbers of replicating molecules accumulate, indicating that inhibition by EthBr primarily affects...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 1994
ISSN: 0006-2952
DOI: 10.1016/0006-2952(94)90326-3